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Ade Whitehouse

Position
Professor of Molecular Virology
Areas of expertise
Infectious diseases and cancer
Faculty
Biological Sciences
School
Molecular and Cellular Biology

Countries

South Africa

Research

My research investigates the link between viruses and cancer. I collaborate with colleagues in South Africa due to the high prevalence of HIV in the region, which significantly impacts cancer patterns there.

At my laboratory in Leeds, we focus on the molecular biology of the two most recently identified human tumor viruses: Kaposi’s sarcoma-associated herpesvirus (KSHV) and Merkel cell polyomavirus (MCPyV).

KSHV is linked to several lymphoproliferative disorders, including Kaposi’s sarcoma (KS), which has become much more widespread in Africa as a result of the HIV epidemic. Today, KS is the most common cancer among adults in sub-Saharan Africa. Despite this, there are no KSHV-targeted antivirals or vaccines.


Training Initiative

In collaboration with the Universities of Rhodes and Cape Town, we have formed a consortium to train early-stage researchers in infectious diseases and rational drug discovery/design.

Our long-term goal is to develop novel therapeutic strategies for major infectious diseases affecting sub-Saharan Africa.

The project focuses on capacity building, knowledge exchange, and promoting interdisciplinary research.